From Halopedia, the Halo wiki
Following its commissioning, the Panama was deployed to defend a vital fuel and power processing station against an attack by Covenant remnant forces deploying from the CAS-class assault carrier Purveyor of Virtue. The Panama deployed its energy-based armaments against the carrier, but was unable to score critical damage. However, Purveyor of Virtue was also unable to retaliate against the Panama with its full power, for fear of destroying the objective it was intended to exploit, leaving the two ships in a tense stalemate.
At some point, the Panama encountered a network of Banished Gorespike cannons after being separated from its battle group. The frigate was forced into the cannons' killbox by squadrons of Banished hunter-killer warships. Attempting to buy time for the frigate to find cover or evacuate its supplies and crew, Spartan ground teams were deployed in a last-ditch effort to cripple or destroy the control node for the cannon network to allow the Panama to escape.
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