On January 1st, 2537, almost six years after the Battle of the Etran Harborage, Maldini was awoken from cryosleep by Serina in order to perform routine operations and maintenance on the Spirit of Fire. After checking on the ship's life support systems, engines and reactor, Maldini proceeded to inspect Cryo-bay Foxtrot 7. As Maldini completed and logged her inspection, she was attacked by a stowaway Pod infector and was overtaken by the parasite. Serina, having begun the early stages of rampancy, failed to take full measures and instead locked the resultant combat form in the cryo-bay for study. After three days of study and observation, Serina witnessed the infected enter the carrier stage and spawn more infection forms. Able to absorb a host's knowledge, the Flood utilized Maldini's knowledge of cryo chamber codes to awaken and infect more crew members. The resulting Flood infestation aboard the ship was ultimately eradicated due to the efforts of Serina, Professor Ellen Anders, and Spartan Jerome-092.
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