Infection Form

The Infection Form is the first stage of the Flood. It is considered to be the organism's "natural" state. It is also referred to as the "spore form".

Background
The spore Flood form is nearly harmless at first glance, but once it gains physical contact with a biological host it becomes highly virulent. Small tendrils underneath its "body" penetrate the skin and unleash an attack on the host's nervous system. First, it paralyzes the host's body. Once this is accomplished, it rewrites the neural pathways of the victim's brain with it's tendrils, forcing a resonant frequency match between its neural signals and the host's. Then it releases Flood DNA which overwrites host DNA and causes the host to mutate. When this is done, it starts to edge its way into the body, slowly moving organs out of the way so it can nest itself into the chest cavity of its host. If a match cannot be obtained, the host is left alone but it is most likely that they will probably kill it (if its not dead aleady) and save the host's body later for sustanance.

At this time, the only known human subject to be incompatible with Flood Infection Forms is Sergeant Johnson, due to his contracting Boren's Syndrome from the residual radiation of Plasma Grenades. There are theories on other species immunities to the flood, such as the Hunter's lack of a central nervous system.

Combat
Infection Forms are extremely fragile, and easy to defeat by themselves. Unfortunately, they are never by themselves. Dozens of Infection Forms usually follow Combat Forms and Carrier Forms into battle, infecting new victims while they are wounded or distracted in fighting the other forms.

The easiest weapons to use to destroy them are Assault Rifles, Shotguns, SMGs, and Grenades, as they usually move in swarms and one burst from these weapons can eliminate many of them. If the victim does not have a shield engaged, the forms will latch on to the victim and begin draining its energy. Jumping or other aggressive actions can get them to detach. When faced by mass waves of Infection Forms, the Assault Rifle works due to it's very quick rate of fire. The Forerunners developed the Sentinel Beam to destroy Flood, and it should be used when available, but it is only accessible in Halo 2. In Halo 2, they can revive dead but un-dismembered Combat Forms by burrowing into them, greatly increasing their threat level. Also, the Infection Forms can destroy Sentinels if the former leaps onto the latter. If the player inflicts enough damage to the prone Combat Form it will disintegrate completely and become useless (Grenades/explosives are most effective, Energy Swords and the Brute Shot melee, and the Plasma Rifle are also found to be effective, as unlike the Energy Sword the melee function doesn't have a limited usage amount. The Shotgun is also very effective, on both Human and Covenant Combat Forms).

Trivia

 * The Infection Form has appeared in two Action Figure sets: the Halo 1 Flood Carrier Form Action Figure and the Halo 2 s8 Master Chief v4 Action Figure. The differences between the two versions were significant, namely the first Infection Form featured a detachable membrane that revealed the internal organs of the creature.
 * In Halo: Combat Evolved, the Infection Forms glow in the dark in an on-off fashion.
 * In Halo 2, when a combat form is dismembered but not killed, it will automatically die after a couple seconds and an infection form will spawn out of its chest cavity where it once resided in the host's body.
 * An Energy Sword will not lose energy by killing infection forms.
 * In Halo 1, Infection forms appear in greater numbers, but chain react when destroyed, popping others nearby, this factor was removed in Halo 2, so to make up for it, their numbers were lowered.
 * In Halo 1 if you shine the light from the assault rifle on a infection form flood. It will get out of the way of the light. So you can actually shine the light on them to make a path.