Knock the Prophet of Regret out of his throne

The following steps are a guide to Blow the Prophet of Regret out of his throne.

Walkthrough
1. Get the Sputnik Skull.

2. Play through the level Regret on any difficulty.

3. Get any explosive weapons you can find. The Needler and Fuel Rod Cannon works best.

4. Blast the Prophet of Regret with all of your fire power until his gravity throne flips over.

5. The Prophet of Regret will shoot his Plasma Pistol at you. He will teleport after 10 seconds back to his gravity throne.